N-Acetyl-l-cysteine and aminooxyacetic acid differentially modulate trichloroethylene reproductive toxicity via metabolism in Wistar rats

Exposure to the industrial solvent trichloroethylene (TCE) has been associated with adverse pregnancy outcomes in humans and decreased fetal weight in rats. TCE kidney toxicity can occur through formation of reactive metabolites via its glutathione (GSH) conjugation metabolic pathway, largely unstud...

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Vydáno v:Arch Toxicol
Hlavní autoři: Su, Anthony L., Lash, Lawrence H., Bergin, Ingrid L., Bjork, Faith, Loch-Caruso, Rita
Médium: Artigo
Jazyk:Inglês
Vydáno: 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8035313/
https://ncbi.nlm.nih.gov/pubmed/33599830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-021-02991-8
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