Colonic epithelial-derived Selenoprotein P is the source for antioxidant-mediated protection in colitis-associated cancer

BACKGROUND AND AIMS: Patients with inflammatory bowel disease (IBD) demonstrate nutritional selenium deficiencies and are at greater risk for colon cancer. Previously, we determined that global reduction of the secreted antioxidant selenium-containing protein, Selenoprotein P (SELENOP), substantiall...

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Publicado no:Gastroenterology
Main Authors: Short, Sarah P., Pilat, Jennifer M., Barrett, Caitlyn W., Reddy, Vishruth K., Haberman, Yael, Hendren, Jared R., Marsh, Benjamin J., Keating, Cody E., Motley, Amy K., Hill, Kristina E., Zemper, Anne. E., Washington, M. Kay, Shi, Chanjuan, Chen, Xi, Wilson, Keith T., Hyams, Jeffrey S., Denson, Lee A., Burk, Raymond F., Rosen, Michael J., Williams, Christopher S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8035252/
https://ncbi.nlm.nih.gov/pubmed/33388316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2020.12.059
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