Colonic epithelial-derived Selenoprotein P is the source for antioxidant-mediated protection in colitis-associated cancer

BACKGROUND AND AIMS: Patients with inflammatory bowel disease (IBD) demonstrate nutritional selenium deficiencies and are at greater risk for colon cancer. Previously, we determined that global reduction of the secreted antioxidant selenium-containing protein, Selenoprotein P (SELENOP), substantiall...

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Veröffentlicht in:Gastroenterology
Hauptverfasser: Short, Sarah P., Pilat, Jennifer M., Barrett, Caitlyn W., Reddy, Vishruth K., Haberman, Yael, Hendren, Jared R., Marsh, Benjamin J., Keating, Cody E., Motley, Amy K., Hill, Kristina E., Zemper, Anne. E., Washington, M. Kay, Shi, Chanjuan, Chen, Xi, Wilson, Keith T., Hyams, Jeffrey S., Denson, Lee A., Burk, Raymond F., Rosen, Michael J., Williams, Christopher S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8035252/
https://ncbi.nlm.nih.gov/pubmed/33388316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2020.12.059
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