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Zinc Dependent Regulation of ZEB1 and YAP1 Co-activation Promotes EMT Plasticity and Metastasis in Pancreatic Cancer

BACKGROUND: Pancreatic cancer is characterized by extensive metastasis. EMT plasticity plays a critical role in tumor progression and metastasis by maintaining the transition between EMT and MET states. Our aim is to understand the molecular events regulating metastasis and EMT plasticity in pancrea...

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發表在:Gastroenterology
Main Authors: Liu, Mingyang, Zhang, Yuqing, Yang, Jingxuan, Zhan, Hanxiang, Zhou, Zhijun, Jiang, Yuanyuan, Shi, Xiuhui, Fan, Xiao, Zhang, Junxia, Luo, Wenyi, Fung, Kar-Ming A., Xu, Chao, Bronze, Michael S., Houchen, Courtney W., Li, Min
格式: Artigo
語言:Inglês
出版: 2021
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8035249/
https://ncbi.nlm.nih.gov/pubmed/33421513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2020.12.077
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