An integrated model of N6-methyladenosine regulators to predict tumor aggressiveness and immune evasion in pancreatic cancer

BACKGROUND: N6-methyladenosine (m6A) is the most abundant mRNA modification. Whether m6A regulators can determine tumor aggressiveness and risk of immune evasion in pancreatic ductal adenocarcinoma (PDAC) remains unknown. METHODS: An integrated model named “m6Ascore” is constructed based on RNA-seq...

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Detalles Bibliográficos
Publicado en:EBioMedicine
Main Authors: Zhou, Zhijun, Zhang, Junxia, Xu, Chao, Yang, Jingxuan, Zhang, Yuqing, Liu, Mingyang, Shi, Xiuhui, Li, Xiaoping, Zhan, Hanxiang, Chen, Wei, McNally, Lacey R., Fung, Kar-Ming, Luo, Wenyi, Houchen, Courtney W., He, Yulong, Zhang, Changhua, Li, Min
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2021
Assuntos:
Research paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7966986/
https://ncbi.nlm.nih.gov/pubmed/33714027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2021.103271
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