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The activity of yeast Apn2 AP endonuclease at uracil-derived AP sites is dependent on the major carbon source

Yeast Apn2 is an AP endonuclease and DNA 3′-diesterase that belongs to the Exo III family with homology to the E. coli exonuclease III, Schizosaccharomyces pombe eth1, and human AP endonucleases APEX1 and APEX2. In the absence of Apn1, the major AP endonuclease in yeast, Apn2 can cleave the DNA back...

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Veröffentlicht in:Curr Genet
Hauptverfasser: Stokdyk, Kasey, Berroyer, Alexandra, Grami, Zacharia A., Kim, Nayun
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8035244/
https://ncbi.nlm.nih.gov/pubmed/33386486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00294-020-01141-4
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