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Chronic caloric restriction maintains a youthful phosphoproteome in aged skeletal muscle

Caloric restriction (CR) can prolong aged skeletal muscle function, yet the molecular mechanisms are not completely understood. We performed phosphoproteomic analysis on muscle from young and old mice fed an ad libitum diet, and old mice fed a CR diet. CR promoted a youthful phosphoproteomic signatu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mech Ageing Dev
Hauptverfasser: Bareja, Akshay, Draper, James A., Katz, Lauren H., Lee, David E., Grimsrud, Paul A., White, James P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8035222/
https://ncbi.nlm.nih.gov/pubmed/33529682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2021.111443
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