Indispensable role of Galectin-3 in promoting quiescence of hematopoietic stem cells

Hematopoietic stem cells (HSCs) in adult bone marrow (BM) are usually maintained in a state of quiescence. The cellular mechanism coordinating the balance between HSC quiescence and differentiation is not fully understood. Here, we report that galactose-binding lectin-3 (galectin-3; Gal-3) is upregu...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Jia, Weizhen, Kong, Lingyu, Kidoya, Hiroyasu, Naito, Hisamichi, Muramatsu, Fumitaka, Hayashi, Yumiko, Hsieh, Han-Yun, Yamakawa, Daishi, Hsu, Daniel K., Liu, Fu-Tong, Takakura, Nobuyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8035175/
https://ncbi.nlm.nih.gov/pubmed/33837181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22346-2
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