mTOR inhibition improves mitochondria function/biogenesis and delays cardiovascular aging in kidney transplant recipients with chronic graft dysfunction

CVD remains the major cause of mortality with graft functioning in Kidney transplant recipients (KTRs), with an estimated risk of CV events about 50-fold higher than in the general population. Many strategies have been considered to reduce the CV risk such as the use of mTOR inhibitors. We evaluate...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Infante, Barbara, Bellanti, Francesco, Correale, Michele, Pontrelli, Paola, Franzin, Rossana, Leo, Serena, Calvaruso, Martina, Mercuri, Silvia, Netti, Giuseppe Stefano, Ranieri, Elena, Brunetti, Natale Daniele, Grandaliano, Giuseppe, Gesualdo, Loreto, Serviddio, Gaetano, Castellano, Giuseppe, Stallone, Giovanni
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2021
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8034974/
https://ncbi.nlm.nih.gov/pubmed/33758105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.202863
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