Dynamic extrinsic pacing of the HOX clock in human axial progenitors controls motor neuron subtype specification

Rostro-caudal patterning of vertebrates depends on the temporally progressive activation of HOX genes within axial stem cells that fuel axial embryo elongation. Whether the pace of sequential activation of HOX genes, the 'HOX clock', is controlled by intrinsic chromatin-based timing mechan...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Mouilleau, Vincent, Vaslin, Célia, Robert, Rémi, Gribaudo, Simona, Nicolas, Nour, Jarrige, Margot, Terray, Angélique, Lesueur, Léa, Mathis, Mackenzie W., Croft, Gist, Daynac, Mathieu, Rouiller-Fabre, Virginie, Wichterle, Hynek, Ribes, Vanessa, Martinat, Cécile, Nedelec, Stéphane
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2021
Assuntos:
Human Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8034877/
https://ncbi.nlm.nih.gov/pubmed/33782043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.194514
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