A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures

Coronaviruses are prone to emergence into new host species most recently evidenced by SARS-CoV-2, the causative agent of the COVID-19 pandemic(1). Small animal models that recapitulate SARS-CoV-2 disease are desperately needed to rapidly evaluate medical countermeasures (MCMs)(2,3). SARS-CoV-2 canno...

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Publicado en:Nature
Main Authors: Dinnon, Kenneth H., Leist, Sarah R., Schäfer, Alexandra, Edwards, Caitlin E., Martinez, David R., Montgomery, Stephanie A., West, Ande, Yount, Boyd L., Hou, Yixuan J., Adams, Lily E., Gully, Kendra L., Brown, Ariane J., Huang, Emily, Bryant, Matthew D., Choong, Ingrid C., Glenn, Jeffrey S., Gralinski, Lisa E., Sheahan, Timothy P., Baric, Ralph S.
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8034761/
https://ncbi.nlm.nih.gov/pubmed/32854108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-2708-8
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