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The Human Fragile X Mental Retardation Protein Inhibits the Elongation Step of Translation through its RGG and C-terminal domains

Fragile X mental retardation protein (FMRP) is an RNA-binding protein that regulates the translation of numerous mRNAs in neurons. The precise mechanism of translational regulation by FMRP is unknown. Some studies have indicated that FMRP inhibits the initiation step of translation, whereas other st...

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Bibliografske podrobnosti
izdano v:Biochemistry
Main Authors: Athar, Youssi M., Joseph, Simpson
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8034582/
https://ncbi.nlm.nih.gov/pubmed/32945655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.0c00534
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