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RNA-Binding Specificity of the Human Fragile X Mental Retardation Protein

Fragile X syndrome (FXS) is the most common form of inherited intellectual disability and is caused by a deficiency of the fragile X mental retardation protein (FMRP) in neurons. FMRP regulates the translation of numerous mRNAs within dendritic synapses, but how FMRP recognizes these target mRNAs re...

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Publié dans:J Mol Biol
Auteurs principaux: Athar, Youssi M., Joseph, Simpson
Format: Artigo
Langue:Inglês
Publié: 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7306444/
https://ncbi.nlm.nih.gov/pubmed/32343993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2020.04.021
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