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Cardiomyocyte protective effects of thyroid hormone during hypoxia/reoxygenation injury through activating of IGF‐1‐mediated PI3K/Akt signalling

Ischaemia/reperfusion (I/R) injury is a common clinical condition that results in apoptosis and oxidative stress injury. Thyroid hormone was previously reported to elicit cardiac myocyte hypertrophy and promote cardiac function after cardiac injury. We used an in vivo mouse model of I/R injury and i...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Zeng, Bin, Liu, Lei, Liao, Xiaoting, Zhang, Caixia
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8034470/
https://ncbi.nlm.nih.gov/pubmed/33724692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.16389
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