FGF19 protects skeletal muscle against obesity‐induced muscle atrophy, metabolic derangement and abnormal irisin levels via the AMPK/SIRT‐1/PGC‐α pathway

Obesity is associated with biological dysfunction in skeletal muscle. As a condition of obesity accompanied by muscle mass loss and physical dysfunction, sarcopenic obesity (SO) has become a novel public health problem. Human fibroblast growth factor 19 (FGF19) plays a therapeutic role in metabolic...

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Veröffentlicht in:J Cell Mol Med
Hauptverfasser: Guo, Ai, Li, Kai, Tian, Hong‐Chuan, Fan, Zhen, Chen, Qiu‐Nan, Yang, Yun‐Fei, Yu, Jing, Wu, Yong‐Xin, Xiao, Qian
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2021
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8034456/
https://ncbi.nlm.nih.gov/pubmed/33751819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.16448
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