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Undifferentiated colonic neoplasm with SMARCA4 germline gene mutation and loss of SMARCA4 protein expression: a case report and literature review

BACKGROUND: Nonsense mutation or inactivation of SMARCA4 (BRG1) is associated with a monomorphic undifferentiated histological appearance in tumors at different sites. The association between SMARCA4 alteration and undifferentiated colonic carcinoma needs to be further elucidated. METHODS: A 61-year...

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Detalhes bibliográficos
Publicado no:Diagn Pathol
Main Authors: Duan, Huanli, Gao, Wei, Wang, Leiming, Cao, Feng, Teng, Lianghong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8033741/
https://ncbi.nlm.nih.gov/pubmed/33836796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13000-021-01091-6
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