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Inhibition of P-Glycoprotein Does Not Increase the Efficacy of Proteasome Inhibitors in Multiple Myeloma Cells

[Image: see text] P-Glycoprotein is a well-known drug transporter associated with chemotherapy resistance in a number of cancers, but its role in modulating proteasome inhibitor efficacy in multiple myeloma is not well understood. The second-generation proteasome inhibitor carfilzomib is thought to...

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Publicado en:ACS Pharmacol Transl Sci
Autores principales: Mynott, Rachel L., Wallington-Beddoe, Craig T.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Chemical Society 2021
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8033612/
https://ncbi.nlm.nih.gov/pubmed/33860196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.0c00200
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