Targeting netrin‐3 in small cell lung cancer and neuroblastoma

The navigation cue netrin‐1 is well‐documented for its key role in cancer development and represents a promising therapeutic target currently under clinical investigation. Phase 1 and 2 clinical trials are ongoing with NP137, a humanized monoclonal antibody against netrin‐1. Interestingly, the epito...

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Publicat a:EMBO Mol Med
Autors principals: Jiang, Shan, Richaud, Mathieu, Vieugué, Pauline, Rama, Nicolas, Delcros, Jean‐Guy, Siouda, Maha, Sanada, Mitsuaki, Redavid, Anna‐Rita, Ducarouge, Benjamin, Hervieu, Maëva, Breusa, Silvia, Manceau, Ambroise, Gattolliat, Charles‐Henry, Gadot, Nicolas, Combaret, Valérie, Neves, David, Ortiz‐Cuaran, Sandra, Saintigny, Pierre, Meurette, Olivier, Walter, Thomas, Janoueix‐Lerosey, Isabelle, Hofman, Paul, Mulligan, Peter, Goldshneider, David, Mehlen, Patrick, Gibert, Benjamin
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2021
Matèries:
Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8033513/
https://ncbi.nlm.nih.gov/pubmed/33719214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.202012878
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