AB018. Myeloid dendritic cells (mDCs) are major producers of interferon-beta in dermatomyositis and increased numbers of mDCs are found in hydroxychloroquine nonresponders

BACKGROUND: Dermatomyositis (DM) is an autoimmune disease affecting skin, skeletal muscle, and lungs. Pathogenesis is considered largely driven by interferon-beta (IFN-beta) and involves CD4+ cells and dendritic cells (DCs). (I) Quantify inflammatory cells and IFN-beta in skin; correlate with Cutane...

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Publicado en:Ann Transl Med
Autores principales: Chen, Kristen L., Zeidi, Majid, Wysocka, Maria, Reddy, Nithin, Jadoo, Arvin, Bashir, Muhammad M., Ahmed, Sarah, Patel, Basil, Zhang, Kevin K., White, Barbara, Werth, Victoria P.
Formato: Artigo
Lenguaje:Inglês
Publicado: AME Publishing Company 2021
Materias:
Abstract on Rheumatologic Skin Disease
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8033346/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm.2021.AB018
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