GYY4137 and Sodium Hydrogen Sulfide Relaxations Are Inhibited by L-Cysteine and K(V)7 Channel Blockers in Rat Small Mesenteric Arteries

Donors of H(2)S may be beneficial in treating cardiovascular diseases where the plasma levels of H(2)S are decreased. Therefore, we investigated the mechanisms involved in relaxation of small arteries induced by GYY4137 [(4-methoxyphenyl)-morpholin-4-yl-sulfanylidene-sulfido-λ5-phosphane;morpholin-4...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Abramavicius, Silvijus, Petersen, Asbjørn G., Renaltan, Nirthika S., Prat-Duran, Judit, Torregrossa, Roberta, Stankevicius, Edgaras, Whiteman, Matthew, Simonsen, Ulf
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8032876/
https://ncbi.nlm.nih.gov/pubmed/33841145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.613989
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