GYY4137 and Sodium Hydrogen Sulfide Relaxations Are Inhibited by L-Cysteine and K(V)7 Channel Blockers in Rat Small Mesenteric Arteries

Donors of H(2)S may be beneficial in treating cardiovascular diseases where the plasma levels of H(2)S are decreased. Therefore, we investigated the mechanisms involved in relaxation of small arteries induced by GYY4137 [(4-methoxyphenyl)-morpholin-4-yl-sulfanylidene-sulfido-λ5-phosphane;morpholin-4...

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Publicat a:Front Pharmacol
Autors principals: Abramavicius, Silvijus, Petersen, Asbjørn G., Renaltan, Nirthika S., Prat-Duran, Judit, Torregrossa, Roberta, Stankevicius, Edgaras, Whiteman, Matthew, Simonsen, Ulf
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
Matèries:
Pharmacology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8032876/
https://ncbi.nlm.nih.gov/pubmed/33841145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.613989
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