The Slow-Releasing Hydrogen Sulfide Donor, GYY4137, Exhibits Novel Anti-Cancer Effects In Vitro and In Vivo

The slow-releasing hydrogen sulfide (H(2)S) donor, GYY4137, caused concentration-dependent killing of seven different human cancer cell lines (HeLa, HCT-116, Hep G2, HL-60, MCF-7, MV4-11 and U2OS) but did not affect survival of normal human lung fibroblasts (IMR90, WI-38) as determined by trypan blu...

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Autors principals: Lee, Zheng Wei, Zhou, Jianbiao, Chen, Chien-Shing, Zhao, Yujun, Tan, Choon-Hong, Li, Ling, Moore, Philip Keith, Deng, Lih-Wen
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119065/
https://ncbi.nlm.nih.gov/pubmed/21701688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021077
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