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Defective dystrophic thymus determines degenerative changes in skeletal muscle
In Duchenne muscular dystrophy (DMD), sarcolemma fragility and myofiber necrosis produce cellular debris that attract inflammatory cells. Macrophages and T-lymphocytes infiltrate muscles in response to damage-associated molecular pattern signalling and the release of TNF-α, TGF-β and interleukins pr...
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| Publié dans: | Nat Commun |
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| Auteurs principaux: | , , , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2021
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8032677/ https://ncbi.nlm.nih.gov/pubmed/33833239 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22305-x |
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