Defective dystrophic thymus determines degenerative changes in skeletal muscle

In Duchenne muscular dystrophy (DMD), sarcolemma fragility and myofiber necrosis produce cellular debris that attract inflammatory cells. Macrophages and T-lymphocytes infiltrate muscles in response to damage-associated molecular pattern signalling and the release of TNF-α, TGF-β and interleukins pr...

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Publicat a:Nat Commun
Autors principals: Farini, Andrea, Sitzia, Clementina, Villa, Chiara, Cassani, Barbara, Tripodi, Luana, Legato, Mariella, Belicchi, Marzia, Bella, Pamela, Lonati, Caterina, Gatti, Stefano, Cerletti, Massimiliano, Torrente, Yvan
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8032677/
https://ncbi.nlm.nih.gov/pubmed/33833239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22305-x
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