The neurosteroid allopregnanolone protects retinal neurons by effects on autophagy and GABRs/GABA(A) receptors in rat glaucoma models

In an ex vivo rat glaucoma model using dissected retinas, the neurosteroid allopregnanolone (AlloP) protects retinal ganglion cells (RGCs) via GABR/GABA(A) receptors. To determine the involvement of macroautophagy/autophagy in neuroprotection by AlloP, we examined the effects of autophagy activators...

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Bibliografski detalji
Izdano u:Autophagy
Glavni autori: Ishikawa, Makoto, Takaseki, Sanae, Yoshitomi, Takeshi, Covey, Douglas F., Zorumski, Charles F., Izumi, Yukitoshi
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2020
Teme:
Research Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8032250/
https://ncbi.nlm.nih.gov/pubmed/32070183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2020.1731270
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