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Neurosteroids Are Endogenous Neuroprotectants in an Ex Vivo Glaucoma Model
PURPOSE. Allopregnanolone is a neurosteroid and powerful modulator of neuronal excitability. The neuroprotective effects of allopregnanolone involve potentiation of γ-aminobutyric acid (GABA) inhibitory responses. Although glutamate excitotoxicity contributes to ganglion cell death in glaucoma, the...
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| Publicado no: | Invest Ophthalmol Vis Sci |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Association for Research in Vision and Ophthalmology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4280088/ https://ncbi.nlm.nih.gov/pubmed/25406290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.14-15624 |
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