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Atf-6 Regulates Lifespan through ER-Mitochondrial Calcium Homeostasis
Individually, dysfunction of both the endoplasmic reticulum (ER) and mitochondria has been linked to aging, but how communication between these organelles might be targeted to promote longevity is unclear. Here, we provide evidence that, in Caenorhabditis elegans, inhibition of the conserved unfolde...
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| 出版年: | Cell Rep |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8030272/ https://ncbi.nlm.nih.gov/pubmed/32905769 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.108125 |
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