Dietary Restriction and AMPK Increase Lifespan via Mitochondrial Network and Peroxisome Remodeling

Mitochondrial network remodeling between fused and fragmented states facilitates mitophagy, interaction with other organelles and metabolic flexibility. Aging is associated with a loss of mitochondrial network homeostasis, but cellular processes causally linking these changes to organismal senescenc...

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Publicado en:Cell Metab
Main Authors: Weir, Heather J., Yao, Pallas, Huynh, Frank K., Escoubas, Caroline C., Goncalves, Renata L., Burkewitz, Kristopher, Laboy, Raymond, Hirschey, Matthew D., Mair, William B.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5718936/
https://ncbi.nlm.nih.gov/pubmed/29107506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2017.09.024
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