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Complex Variant Discovery Using Discordant Cluster Normalization

Complex genomic structural variants (CGSVs) are abnormalities that present with three or more breakpoints, making their discovery a challenge. The majority of existing algorithms for structural variant detection are only designed to find simple structural variants (SSVs) such as deletions and invers...

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Detalhes bibliográficos
Publicado no:J Comput Biol
Main Authors: Hayes, Matthew, Mullins, Derrick, Nguyen, Angela
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc., publishers 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8030116/
https://ncbi.nlm.nih.gov/pubmed/32783649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cmb.2020.0249
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