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Structure Activity Relationship Study of the XIP Quorum Sensing Pheromone in Streptococcus mutans Reveal Inhibitors of the Competence Regulon
The dental cariogenic pathogen Streptococcus mutans coordinates competence for genetic transformation via two peptide pheromones, competence stimulating peptide (CSP) and comX-inducing peptide (XIP). CSP is sensed by the comCDE system and induces competence indirectly whereas, XIP is sensed by the c...
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| Published in: | ACS Chem Biol |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2020
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8029583/ https://ncbi.nlm.nih.gov/pubmed/32946208 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.0c00650 |
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