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Structure Activity Relationship Study of the XIP Quorum Sensing Pheromone in Streptococcus mutans Reveal Inhibitors of the Competence Regulon

The dental cariogenic pathogen Streptococcus mutans coordinates competence for genetic transformation via two peptide pheromones, competence stimulating peptide (CSP) and comX-inducing peptide (XIP). CSP is sensed by the comCDE system and induces competence indirectly whereas, XIP is sensed by the c...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:ACS Chem Biol
Main Authors: Bikash, Chowdhury Raihan, Tal-Gan, Yftah
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8029583/
https://ncbi.nlm.nih.gov/pubmed/32946208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.0c00650
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