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The Influenza A Virus H3N2 Triggers the Hypersusceptibility of Airway Inflammatory Response via Activating the lncRNA TUG1/miR-145-5p/NF-κB Pathway in COPD

Background: Patients with chronic obstructive pulmonary disease (COPD) are more susceptible to influenza A virus (IAV) with more severe symptoms, yet the underlying molecular mechanisms of the hypersusceptibility of airway inflammatory response remain unclear. Methods: The primary human bronchial ep...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Tu, You-Hui, Guo, Yan, Ji, Shuang, Shen, Ji-Long, Fei, Guang-He
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8029562/
https://ncbi.nlm.nih.gov/pubmed/33841139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.604590
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