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The mechanism by which imeglimin inhibits gluconeogenesis in rat liver cells

AIMS: To understand the mechanism by which imeglimin (a new oral hypoglycemic agent whose phase 3 development program in Japan has now been completed) decreases hepatic glucose production. MATERIALS AND METHODS: We compared the effect of imeglimin and metformin on glucose production, ATP/ADP ratio,...

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Bibliografiske detaljer
Udgivet i:Endocrinol Diabetes Metab
Main Authors: Vial, Guillaume, Lamarche, Frédéric, Cottet‐Rousselle, Cécile, Hallakou‐Bozec, Sophie, Borel, Anne‐Laure, Fontaine, Eric
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8029524/
https://ncbi.nlm.nih.gov/pubmed/33855213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/edm2.211
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