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Imeglimin preserves islet β‐cell mass in Type 2 diabetic ZDF rats

OBJECTIVES: Type 2 diabetes (T2D) is driven by progressive dysfunction and loss of pancreatic β‐cell mass. Imeglimin is a first‐in‐class novel drug candidate that improves glycaemia and glucose‐stimulated insulin secretion in preclinical models and patients. Given evidence that imeglimin can attenua...

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Detalhes bibliográficos
Publicado no:Endocrinol Diabetes Metab
Main Authors: Hallakou‐Bozec, Sophie, Kergoat, Micheline, Moller, David E., Bolze, Sébastien
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8029531/
https://ncbi.nlm.nih.gov/pubmed/33855202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/edm2.193
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