Ubiquitin is Associated with Early Truncation of Tau Protein at Aspartic Acid(421) during the Maturation of Neurofibrillary Tangles in Alzheimer's Disease

Pathological processing of tau protein during the formation and maturation of neurofibrillary tangles (NFTs) includes abnormal phosphorylation, conformational changes and truncation of the C‐terminus at aspartic‐acid(421) (apoptotic product) and glutamic‐acid(391) residues. Abnormal phosphorylation...

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Detalhes bibliográficos
Publicado no:Brain Pathol
Main Authors: García‐Sierra, Francisco, Jarero‐Basulto, Jose J., Kristofikova, Zdena, Majer, Emerich, Binder, Lester I., Ripova, Daniela
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2011
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8029281/
https://ncbi.nlm.nih.gov/pubmed/21919991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2011.00525.x
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