Canonical TGF‐β Pathway Activity Is a Predictor of SHH‐Driven Medulloblastoma Survival and Delineates Putative Precursors in Cerebellar Development

Medulloblastoma (MB) is the most common malignant brain tumor of childhood. Very little is known about aggressive forms of this disease, such as metastatic or recurrent MBs. In order to identify pathways involved in aggressive MB pathophysiology, we performed unbiased, whole genome microarrays on MB...

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Vydáno v:Brain Pathol
Hlavní autoři: Aref, Donya, Moffatt, Connor J., Agnihotri, Sameer, Ramaswamy, Vijay, Dubuc, Adrian M., Northcott, Paul A., Taylor, Michael D., Perry, Arie, Olson, James M., Eberhart, Charles G., Croul, Sidney E.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2012
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8029114/
https://ncbi.nlm.nih.gov/pubmed/22966790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2012.00631.x
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