Canonical TGF‐β Pathway Activity Is a Predictor of SHH‐Driven Medulloblastoma Survival and Delineates Putative Precursors in Cerebellar Development

Medulloblastoma (MB) is the most common malignant brain tumor of childhood. Very little is known about aggressive forms of this disease, such as metastatic or recurrent MBs. In order to identify pathways involved in aggressive MB pathophysiology, we performed unbiased, whole genome microarrays on MB...

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Dettagli Bibliografici
Pubblicato in:Brain Pathol
Autori principali: Aref, Donya, Moffatt, Connor J., Agnihotri, Sameer, Ramaswamy, Vijay, Dubuc, Adrian M., Northcott, Paul A., Taylor, Michael D., Perry, Arie, Olson, James M., Eberhart, Charles G., Croul, Sidney E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2012
Soggetti:
Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8029114/
https://ncbi.nlm.nih.gov/pubmed/22966790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2012.00631.x
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