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Rhabdoid Tumors: An Initial Clue to the Role of Chromatin Remodeling in Cancer

The discovery of biallelic, inactivating SMARCB1 mutations in rhabdoid tumors (RTs) over a decade ago represented the first recognized link between chromatin remodeling and tumor suppression. SMARCB1 is a core subunit of the SWI/SNF chromatin remodeling complex, and the recent emergence of frequent...

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Bibliografiske detaljer
Udgivet i:Brain Pathol
Main Authors: Lee, Ryan S., Roberts, Charles W. M.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8029057/
https://ncbi.nlm.nih.gov/pubmed/23432645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12021
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