BRAF‐Mutated Pleomorphic Xanthoastrocytoma is Associated with Temporal Location, Reticulin Fiber Deposition and CD34 Expression

BRAF V600E mutation and homozygous deletion of CDKN2A (p16) are frequent molecular alterations in pleomorphic xanthoastrocytomas (PXAs). We investigated 49 PXAs for clinical, histological and immunohistochemical characteristics related to BRAF mutation status. BRAF mutation was detected by immunohis...

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Dettagli Bibliografici
Pubblicato in:Brain Pathol
Autori principali: Koelsche, Christian, Sahm, Felix, Wöhrer, Adelheid, Jeibmann, Astrid, Schittenhelm, Jens, Kohlhof, Patricia, Preusser, Matthias, Romeike, Bernd, Dohmen‐Scheufler, Hildegard, Hartmann, Christian, Mittelbronn, Michel, Becker, Albert, von Deimling, Andreas, Capper, David
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2014
Soggetti:
Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8029045/
https://ncbi.nlm.nih.gov/pubmed/24345274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12111
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