BRAF‐Mutated Pleomorphic Xanthoastrocytoma is Associated with Temporal Location, Reticulin Fiber Deposition and CD34 Expression

BRAF V600E mutation and homozygous deletion of CDKN2A (p16) are frequent molecular alterations in pleomorphic xanthoastrocytomas (PXAs). We investigated 49 PXAs for clinical, histological and immunohistochemical characteristics related to BRAF mutation status. BRAF mutation was detected by immunohis...

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Detalhes bibliográficos
Publicado no:Brain Pathol
Main Authors: Koelsche, Christian, Sahm, Felix, Wöhrer, Adelheid, Jeibmann, Astrid, Schittenhelm, Jens, Kohlhof, Patricia, Preusser, Matthias, Romeike, Bernd, Dohmen‐Scheufler, Hildegard, Hartmann, Christian, Mittelbronn, Michel, Becker, Albert, von Deimling, Andreas, Capper, David
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2014
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8029045/
https://ncbi.nlm.nih.gov/pubmed/24345274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12111
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