Astrocytes in a dish: Using pluripotent stem cells to model neurodegenerative and neurodevelopmental disorders

Neuroscience and Neurobiology have historically been neuron biased, yet up to 40% of the cells in the brain are astrocytes. These cells are heterogeneous and regionally diverse but universally essential for brain homeostasis. Astrocytes regulate synaptic transmission as part of the tripartite synaps...

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Bibliografiske detaljer
Udgivet i:Brain Pathol
Main Authors: Crompton, Lucy A., Cordero‐Llana, Oscar, Caldwell, Maeve A.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
Fag:
MINI‐SYMPOSIUM: USING iPSCs TO UNDERSTAND HUMAN NEUROLOGICAL DISEASE: POTENTIAL AND LIMITATIONS
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8028895/
https://ncbi.nlm.nih.gov/pubmed/28585380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12522
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