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Targeting neddylation E2s: a novel therapeutic strategy in cancer
Ubiquitin-conjugating enzyme E2 M (UBE2M) and ubiquitin-conjugating enzyme E2 F (UBE2F) are the two NEDD8-conjugating enzymes of the neddylation pathway that take part in posttranslational modification and change the activity of target proteins. The activity of E2 enzymes requires both a 26-residue...
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| 出版年: | J Hematol Oncol |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8028724/ https://ncbi.nlm.nih.gov/pubmed/33827629 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-021-01070-w |
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