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Leukodystrophy caused by plasmalogen deficiency rescued by glyceryl 1‐myristyl ether treatment
Plasmalogens are the most abundant form of ether phospholipids in myelin and their deficiency causes Rhizomelic Chondrodysplasia Punctata (RCDP), a severe developmental disorder. Using the Gnpat‐knockout (KO) mouse as a model of RCDP, we determined the consequences of a plasmalogen deficiency during...
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| Publicado no: | Brain Pathol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8028673/ https://ncbi.nlm.nih.gov/pubmed/30667116 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12710 |
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