Alkyl-Glycerol Rescues Plasmalogen Levels and Pathology of Ether-Phospholipid Deficient Mice

A deficiency of plasmalogens, caused by impaired peroxisomal metabolism affects normal development and multiple organs in adulthood. Treatment options aimed at restoring plasmalogen levels may be relevant for the therapy of peroxisomal and non-peroxisomal disorders. In this study we determined the i...

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Main Authors: Brites, Pedro, Ferreira, Ana Sofia, Ferreira da Silva, Tiago, Sousa, Vera F., Malheiro, Ana R., Duran, Marinus, Waterham, Hans R., Baes, Myriam, Wanders, Ronald J. A.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232224/
https://ncbi.nlm.nih.gov/pubmed/22163031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028539
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