Cytotoxic CD8(+) T cell ablation enhances the capacity of regulatory T cells to delay viral elimination in Theiler's murine encephalomyelitis

Theiler's murine encephalomyelitis (TME) of susceptible mouse strains is a commonly used infectious animal model for multiple sclerosis. The study aim was to test the hypothesis whether cytotoxic T cell responses account for the limited impact of regulatory T cells on antiviral immunity in TME...

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Publicado en:Brain Pathol
Autores principales: Ciurkiewicz, Malgorzata, Herder, Vanessa, Khan, Muhammad Akram, Uhde, Ann‐Kathrin, Teich, René, Floess, Stephan, Baumgärtner, Wolfgang, Huehn, Jochen, Beineke, Andreas
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8028623/
https://ncbi.nlm.nih.gov/pubmed/28452087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12518
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