Viral Infection of the Central Nervous System Exacerbates Interleukin-10 Receptor Deficiency-Mediated Colitis in SJL Mice

Theiler´s murine encephalomyelitis virus (TMEV)-infection is a widely used animal model for studying demyelinating disorders, including multiple sclerosis (MS). The immunosuppressive cytokine Interleukin (IL)-10 counteracts hyperactive immune responses and critically controls immune homeostasis in i...

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Udgivet i:PLoS One
Main Authors: Uhde, Ann-Kathrin, Herder, Vanessa, Akram Khan, Muhammad, Ciurkiewicz, Malgorzata, Schaudien, Dirk, Teich, René, Floess, Stefan, Baumgärtner, Wolfgang, Huehn, Jochen, Beineke, Andreas
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5017624/
https://ncbi.nlm.nih.gov/pubmed/27611574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0161883
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