Downregulated apoptosis and autophagy after anti‐Aβ immunotherapy in Alzheimer's disease

Aβ immunization of Alzheimer's disease (AD) patients in the AN1792 (Elan Pharmaceuticals) trial caused Aβ removal and a decreased density of neurons in the cerebral cortex. As preservation of neurons may be a critical determinant of outcome after Aβ immunization, we have assessed the impact of...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Brain Pathol
Prif Awduron: Paquet, Claire, Nicoll, James AR, Love, Seth, Mouton‐Liger, François, Holmes, Clive, Hugon, Jacques, Boche, Delphine
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2018
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8028546/
https://ncbi.nlm.nih.gov/pubmed/29027727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12567
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