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AMBRA1, a novel α‐synuclein‐binding protein, is implicated in the pathogenesis of multiple system atrophy

The accumulation of abnormal α‐synuclein is the major histopathological feature of Lewy body disease and multiple system atrophy (MSA), which are referred to as synucleinopathies. Cytoplasmic degradation systems, such as the autophagy‐lysosome and proteasome pathways, are involved in their pathogene...

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Bibliographic Details
Published in:Brain Pathol
Main Authors: Miki, Yasuo, Tanji, Kunikazu, Mori, Fumiaki, Tatara, Yota, Utsumi, Jun, Sasaki, Hidenao, Kakita, Akiyoshi, Takahashi, Hitoshi, Fimia, Gian Maria, Wakabayashi, Koichi
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8028368/
https://ncbi.nlm.nih.gov/pubmed/27875637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12461
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