AMBRA1, a novel α‐synuclein‐binding protein, is implicated in the pathogenesis of multiple system atrophy

The accumulation of abnormal α‐synuclein is the major histopathological feature of Lewy body disease and multiple system atrophy (MSA), which are referred to as synucleinopathies. Cytoplasmic degradation systems, such as the autophagy‐lysosome and proteasome pathways, are involved in their pathogene...

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Bibliografiske detaljer
Udgivet i:Brain Pathol
Main Authors: Miki, Yasuo, Tanji, Kunikazu, Mori, Fumiaki, Tatara, Yota, Utsumi, Jun, Sasaki, Hidenao, Kakita, Akiyoshi, Takahashi, Hitoshi, Fimia, Gian Maria, Wakabayashi, Koichi
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8028368/
https://ncbi.nlm.nih.gov/pubmed/27875637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12461
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