Clusterin contributes to early stage of Alzheimer's disease pathogenesis

While clusterin is reportedly involved in Alzheimer's disease (AD) pathogenesis, how clusterin interacts with amyloid‐β (Aß) to cause Aß neurotoxicity remains unclear in vivo. Using 5×FAD transgenic mice, which develop robust AD pathology and memory deficits when very young, we detected interac...

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Detalhes bibliográficos
Publicado no:Brain Pathol
Main Authors: Oh, Shin‐Bi, Kim, Min Sun, Park, SuJi, Son, HyunJu, Kim, Seog‐Young, Kim, Min‐Seon, Jo, Dong‐Gyu, Tak, Eunyoung, Lee, Joo‐Yong
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8028273/
https://ncbi.nlm.nih.gov/pubmed/30295351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12660
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