Clusterin contributes to early stage of Alzheimer's disease pathogenesis

While clusterin is reportedly involved in Alzheimer's disease (AD) pathogenesis, how clusterin interacts with amyloid‐β (Aß) to cause Aß neurotoxicity remains unclear in vivo. Using 5×FAD transgenic mice, which develop robust AD pathology and memory deficits when very young, we detected interac...

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Podrobná bibliografie
Vydáno v:Brain Pathol
Hlavní autoři: Oh, Shin‐Bi, Kim, Min Sun, Park, SuJi, Son, HyunJu, Kim, Seog‐Young, Kim, Min‐Seon, Jo, Dong‐Gyu, Tak, Eunyoung, Lee, Joo‐Yong
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8028273/
https://ncbi.nlm.nih.gov/pubmed/30295351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12660
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