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In vivo comet assay in rabbit corneal epithelial cells following ocular instillation with genotoxic compounds
BACKGROUND: The in vivo comet assay is used to evaluate the genotoxic potential of compounds by detecting DNA strand breaks in cells isolated from animal tissue. The comet assay of hepatocytes is well established; however, the levels of systemic drug exposure following systemic administration are of...
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| Publicado no: | Genes Environ |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8028091/ https://ncbi.nlm.nih.gov/pubmed/33827709 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s41021-021-00184-4 |
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