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Total Synthesis of 6-Hydroxymetatacarboline-d Discovered from Mycena metata via the Pictet–Spengler Reaction Followed by the Horner–Wadsworth–Emmons Reaction

[Image: see text] Total synthesis of a new β-carboline alkaloid, 6-hydroxymetatacarboline-d, which was isolated from fruiting bodies of Mycena metata was accomplished in 14 steps. The synthetic strategy features the Pictet–Spengler reaction to construct the tricyclic core followed by amide coupling...

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Publié dans:ACS Omega
Auteurs principaux: Kumar, Deepak, Vaya, Dipti, Chundawat, Tejpal Singh
Format: Artigo
Langue:Inglês
Publié: American Chemical Society 2021
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8028005/
https://ncbi.nlm.nih.gov/pubmed/33842763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.0c06202
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