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Route to α-Aryl Phosphonoacetates: Useful Synthetic Precursors in the Horner–Wadsworth–Emmons Olefination

[Image: see text] A versatile and general catalytic strategy has been developed for the α-arylation of phosphonoacetates utilizing parallel microscale experimentation. These α-substituted phosphonoacetates are widely useful, notably as substrates in the Horner–Wadsworth–Emmons-type olefinations. How...

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Detalhes bibliográficos
Publicado no:J Org Chem
Main Authors: VanGelder, Kelsey F., Wang, Melinda, Kozlowski, Marisa C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2015
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4612770/
https://ncbi.nlm.nih.gov/pubmed/26405824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.5b01887
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